We do not always know why such things as sickness and setbacks happen to us, for our minds are far too puny to grasp God's plan. A person is a little like a mouse in a piano, which cannot understand why it must be disturbed by someone playing Chopin and forcing it to move off the piano wires.

"Consider him who endured such hostility against himself from sinners, so that you may not grow weary or lose heart." - Hebrews 12:3